SIM-6080
Code | Size | Price |
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TAR-T28779-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28779-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28779-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
SIM-6080 is a calcium channel antagonist. SIM-6080 inhibits the proliferation of rat aortic myocytes.
CAS:
118790-68-4
Formula:
C29H36F2N2O3
Molecular Weight:
498.615
Purity:
0.98
SMILES:
COc1cc(CN(C)CCN(C)CCC(c2ccc(F)cc2)c2ccc(F)cc2)cc(OC)c1OC
References
1. Castelnovo P. Determination of the calcium antagonist SIM6080 and its N- and O-demethylated metabolites in plasma, urine and tissues by high-performance liquid chromatography. J Chromatogr B Biomed Appl. 1996 Feb 9;676(1):77-85. PubMed PMID: 8852047.
2. Castelnovo P. Determination of the calcium antagonist SIM6080 in plasma by high-resolution gas chromatography. J Chromatogr. 1994 Feb 11;652(2):240-4. PubMed PMID: 8006110.
3. Maggi FM, Bernini F, Barberi L, Fantoni M, Catapano AL. SIM 6080, a new calcium antagonist, reduces aortic atherosclerosis in cholesterol-fed rabbits. Pharmacol Res. 1993 Oct-Nov;28(3):219-27. PubMed PMID: 8108312.
4. Bernini F, Fantoni M, Corsini A, Fumagalli R. In vitro inhibition of arterial myocyte growth and stimulation of low density lipoprotein metabolism by SIM 6080, a new calcium antagonist. Pharmacol Res. 1990 Jan-Feb;22(1):27-35. PubMed PMID: 2330336.