Sinoporphyrin sodium
| Code | Size | Price |
|---|
| TAR-T28782-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Sinoporphyrin sodium significantly suppressed cell proliferation, promoted early apoptotic response, triggered collapse of F-actin filaments and inhibited cell migration. Sinoporphyrin sodium potentially a treatment for cancer. Sinoporphyrin sodium is also a photosensitizer.
CAS:
1820582-41-9
Formula:
C68H66N8Na4O9
Molecular Weight:
1231.286
Purity:
0.98
SMILES:
[Na-].[Na-].[Na-].[Na-].CC(OC(C)c1c(C)c2cc3nc(cc4[nH]c(cc5nc(cc1[nH]2)c(C)c5CCC([O-])=O)c(CCC([O-])=O)c4C)c(C)c3C=C)c1c(C)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C)c5CCC([O-])=O)c(CCC([O-])=O)c4C)c(C)c3C=C
References
1. Shi R, Li C, Jiang Z, Li W, Wang A, Wei J. Preclinical Study of Antineoplastic Sinoporphyrin Sodium-PDT via In Vitro and In Vivo Models. Molecules. 2017 Jan 11;22(1). pii: E112. doi: 10.3390/molecules22010112. PubMed PMID: 28085075.
2. Shi R, Lin X, Zhang J, Jin H, Wang A, Wei J. Safety evaluation of repeated intravenous infusion of sinoporphyrin with and without PDT in rats. Photochem Photobiol Sci. 2016 Nov 2;15(11):1366-1376. PubMed PMID: 27714312.
3. Wu L, Wang X, Liu Q, Wingnang Leung A, Wang P, Xu C. Sinoporphyrin sodium mediated photodynamic therapy inhibits the migration associated with collapse of F-actin filaments cytoskeleton in MDA-MB-231 cells. Photodiagnosis Photodyn Ther. 2016 Mar;13:58-65. doi: 10.1016/j.pdpdt.2015.12.008. PubMed PMID: 26742781.
4. Yan X, Niu G, Lin J, Jin AJ, Hu H, Tang Y, Zhang Y, Wu A, Lu J, Zhang S, Huang P, Shen B, Chen X. Enhanced fluorescence imaging guided photodynamic therapy of sinoporphyrin sodium loaded graphene oxide. Biomaterials. 2015 Feb;42:94-102. doi: 10.1016/j.biomaterials.2014.11.040. PubMed PMID: 25542797; PubMed Central PMCID: PMC4280503.