SM19712 free acid
| Code | Size | Price |
|---|
| TAR-T28814-5mg | 5mg | £279.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28814-25mg | 25mg | £631.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SM19712 is an inhibitor of nonpeptide endothelin converting enzyme.
CAS:
194542-49-9
Formula:
C18H14ClN5O3S
Molecular Weight:
415.85
Purity:
0.98
SMILES:
Cc1nn(c(NC(=O)NS(=O)(=O)c2ccc(Cl)cc2)c1C#N)-c1ccccc1
References
1. Hasdemir B, Mahajan S, Bunnett NW, Liao M, Bhargava A. Endothelin-converting enzyme-1 actions determine differential trafficking and signaling of corticotropin-releasing factor receptor 1 at high agonist concentrations. Mol Endocrinol. 2012 Apr;26(4):681-95. doi: 10.1210/me.2011-1361. Epub 2012 Feb 9. PubMed PMID: 22322595; PubMed Central PMCID: PMC3327357.
2. Pelayo JC, Poole DP, Steinhoff M, Cottrell GS, Bunnett NW. Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones. J Physiol. 2011 Nov 1;589(Pt 21):5213-30. doi: 10.1113/jphysiol.2011.214452. Epub 2011 Aug 30. PubMed PMID: 21878523; PubMed Central PMCID: PMC3225675.