SNAP 398299
| Code | Size | Price |
|---|
| TAR-T28822-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28822-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28822-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SNAP 398299, a galanin receptor antagonist, is a potential novel pharmacological treatment for mood disorders.
CAS:
903878-06-8
Formula:
C27H24F3N3O2
Molecular Weight:
479.503
Purity:
0.98
SMILES:
FC(F)(F)c1cccc(c1)N=C1/C(=O)N(c2ccccc12)c1cccc(OCCN2CCCC2)c1
References
1. Scheller KJ, Williams SJ, Lawrence AJ, Jarrott B, Djouma E. An improved method to prepare an injectable microemulsion of the galanin-receptor 3 selective antagonist, SNAP 37889, using Kolliphor(?) HS 15. MethodsX. 2014 Sep 26;1:212-6. doi: 10.1016/j.mex.2014.09.003. eCollection 2014. PubMed PMID: 26150955; PubMed Central PMCID: PMC4472996.
2. Kothandan G, Gadhe CG, Cho SJ. Theoretical characterization of galanin receptor type 3 (Gal3 ) and its interaction with agonist (GALANIN) and antagonists (SNAP 37889 and SNAP 398299): an in silico analysis. Chem Biol Drug Des. 2013 Jun;81(6):757-74. doi: 10.1111/cbdd.12128. Epub 2013 Apr 17. PubMed PMID: 23461969.
3. Ogren SO, Kuteeva E, H?kfelt T, Kehr J. Galanin receptor antagonists : a potential novel pharmacological treatment for mood disorders. CNS Drugs. 2006;20(8):633-54. Review. PubMed PMID: 16863269.
4. Swanson CJ, Blackburn TP, Zhang X, Zheng K, Xu ZQ, H?kfelt T, Wolinsky TD, Konkel MJ, Chen H, Zhong H, Walker MW, Craig DA, Gerald CP, Branchek TA. Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17489-94. Epub 2005 Nov 15. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14978. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5632. PubMed PMID: 16287967; PubMed Central PMCID: PMC1283534.