ST-148
| Code | Size | Price |
|---|
| TAR-T28860-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28860-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28860-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
ST-148 is a potent inhibitor for Dengue virus capsid. ST-148-enhanced capsid protein self-interaction perturbs assembly and disassembly of DV nucleocapsids, probably by inducing structural rigidity.
CAS:
400863-77-6
Formula:
C21H19N5OS2
Molecular Weight:
421.54
Purity:
0.98
SMILES:
Nc1c(sc2nc3CCCCCc3cc12)C(=O)Nc1nnc(s1)-c1ccccc1
References
1. Finkelman MD, Jamison RN, Kulich RJ, Butler SF, Jackson WC, Smits N, Weiner SG. Cross-validation of short forms of the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R). Drug Alcohol Depend. 2017 Sep 1;178:94-100. doi: 10.1016/j.drugalcdep.2017.04.016. Epub 2017 Jun 13. PubMed PMID: 28645065.
2. Scaturro P, Trist IM, Paul D, Kumar A, Acosta EG, Byrd CM, Jordan R, Brancale A, Bartenschlager R. Characterization of the mode of action of a potent dengue virus capsid inhibitor. J Virol. 2014 Oct;88(19):11540-55. doi: 10.1128/JVI.01745-14. Epub 2014 Jul 23. PubMed PMID: 25056895; PubMed Central PMCID: PMC4178822.
3. Byrd CM, Dai D, Grosenbach DW, Berhanu A, Jones KF, Cardwell KB, Schneider C, Wineinger KA, Page JM, Harver C, Stavale E, Tyavanagimatt S, Stone MA, Bartenschlager R, Scaturro P, Hruby DE, Jordan R. A novel inhibitor of dengue virus replication that targets the capsid protein. Antimicrob Agents Chemother. 2013 Jan;57(1):15-25. doi: 10.1128/AAC.01429-12. Epub 2012 Oct 15. PubMed PMID: 23070172; PubMed Central PMCID: PMC3535982.
4. Weber B, Schlicker E, Sokoloff P, Stark H. Identification of the dopamine autoreceptor in the guinea-pig retina as D(2) receptor using novel subtype-selective antagonists. Br J Pharmacol. 2001 Aug;133(8):1243-8. PubMed PMID: 11498509; PubMed Central PMCID: PMC1621144.