Sulcardine sulfate
| Code | Size | Price |
|---|
| TAR-T28879-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28879-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28879-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Sulcardine sulfate, a multi-ion channel blocker, is used potentially for the treatment of arrhythmia.
CAS:
343935-61-5
Formula:
C24H35N3O8S2
Molecular Weight:
557.68
Purity:
0.98
SMILES:
OS(O)(=O)=O.COc1ccc(cc1)S(=O)(=O)NCc1cc(CN2CCCC2)c(O)c(CN2CCCC2)c1
References
1. Wang W, Qian HJ, Xin L, Zhang MQ, Lu DY, Jin JM, Liu GY, Jia JY, Zheng HC, Yu C, Wang YP, Zhu F, Liu Y. Multiple Dose Pharmacokinetics and Safety of Sulcardine Sulfate in Healthy Chinese Male Subjects: An Open-Label Phase I Clinical Study. Eur J Drug Metab Pharmacokinet. 2016 Aug 22. [Epub ahead of print] PubMed PMID: 27550655.
2. Jia J, Liu G, Zhang M, Lu Y, Lu C, Liu Y, Zheng H, Wang W, Gui Y, Yu C, Li S, Wang Y. Determination of the novel antiarrhythmic drug sulcardine sulfate in human plasma by liquid chromatography tandem mass spectrometry and its application in a clinical pharmacokinetic study. Biomed Chromatogr. 2016 Aug;30(8):1291-6. doi: 10.1002/bmc.3681. PubMed PMID: 26715470.
3. Chen Q, Qian HJ, Wang W, Zhang MQ, Lu DY, Lu C, Jin JM, Hu CY, Liu GY, Jia JY, Zheng HC, Li XN, Yu C, Wang YP, Liu Y. Pharmacokinetics, safety, and tolerability of sulcardine sulfate: an open-label, single-dose, randomized study in healthy Chinese subjects. Fundam Clin Pharmacol. 2017 Feb;31(1):120-125. doi: 10.1111/fcp.12242. PubMed PMID: 27599871.
4. Lu YL, Li SJ, Liu GY, Li XC, Yang D, Jia JY, Zhang MQ, Zheng HC, Yu C, Zhu F, Wang YP. Oral Bioavailability and Mass Balance Studies of a Novel Anti-arrhythmic Agent Sulcardine Sulfate in Sprague-Dawley Rats and Beagle Dogs. Eur J Drug Metab Pharmacokinet. 2016 Jul 11. [Epub ahead of print] PubMed PMID: 27402487.