Sulmazole
Code | Size | Price |
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TAR-T28881-1mg | 1mg | £96.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28881-5mg | 5mg | £128.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28881-10mg | 10mg | £156.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28881-25mg | 25mg | £213.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28881-50mg | 50mg | £284.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28881-100mg | 100mg | £389.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28881-500mg | 500mg | £830.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Sulmazole is a positive inotrope sulmazole. Sulmazole inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover. Sulmazole activates the sheep cardiac muscle sarcoplasmic reticulum calcium-release channel in the presence and absence of calcium.
CAS:
73384-60-8
Formula:
C14H13N3O2S
Molecular Weight:
287.34
Pathway:
Metabolism|Microbiology/Virology|GPCR/G Protein|Neuroscience
Purity:
0.98
SMILES:
COc1cc(ccc1-c1nc2ncccc2[nH]1)S(C)=O
Target:
Adenosine Receptor|PDE|Parasite
References
1. Hata K, Goto Y, Futaki S, Takasago T, Saeki A, Nishioka T, Suga H. Effects of milrinone and sulmazole on left ventricular mechanoenergetics in canine hearts. J Card Fail. 1996 Sep;2(3):203-13. PubMed PMID: 8891859.
2. McGarry SJ, Williams AJ. Activation of the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel by analogues of sulmazole. Br J Pharmacol. 1994 Apr;111(4):1212-20. PubMed PMID: 8032608; PubMed Central PMCID: PMC1910124.
3. Verrijk R, Vleeming W, van Rooij HH, Wemer J, Porsius AJ. Positive inotropic effects of milrinone, sulmazole and AR-L100 on isolated normal and infarcted hearts of the rat. Arch Int Pharmacodyn Ther. 1989 Jan-Feb;297:7-17. PubMed PMID: 2730243.
4. Ramkumar V, Stiles GL. The new positive inotrope sulmazole inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover. Mol Pharmacol. 1988 Dec;34(6):761-8. PubMed PMID: 2849044.