TA-270
| Code | Size | Price |
|---|
| TAR-T28907-5mg | 5mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28907-50mg | 50mg | £1,982.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28907-100mg | 100mg | £2,560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
TA-720, a 5-lipoxygenase inhibitor, is used potentially for the treatment of asthma.
CAS:
194037-25-7
Formula:
C29H36N2O7
Molecular Weight:
524.614
Purity:
0.98
SMILES:
CCCCCCCCOc1c(O)c2ccc(NC(=O)C=Cc3cc(OC)c(O)c(OC)c3)cc2n(C)c1=O
References
1. Mizutani N, Aoki Y, Nabe T, Ishiwara M, Yoshino S, Takagaki H, Kohno S. Effect of TA-270, a novel quinolinone derivative, on antigen-induced nasal blockage in a guinea pig model of allergic rhinitis. Eur J Pharmacol. 2009 Jan 5;602(1):138-42. doi: 10.1016/j.ejphar.2008.11.006. PubMed PMID: 19022242.
2. Ishiwara M, Aoki Y, Takagaki H, Ui M, Okajima F. TA-270 [4-hydroxy-1-methyl-3-octyloxy-7-sinapinoylamino-2(1H)-quinolinone], an anti-asthmatic agent, inhibits leukotriene production induced by IgE receptor stimulation in RBL-2H3 cells. J Pharmacol Exp Ther. 2003 Nov;307(2):583-8. PubMed PMID: 12970384.
3. Kimura N, Fukui H, Takagaki H, Yonemochi E, Terada K. Characterization of polymorphs of a novel quinolinone derivative, TA-270 (4-hydroxy-1-methyl-3-octyloxy-7-sinapinoylamino-2(1H)-quinolinone). Chem Pharm Bull (Tokyo). 2001 Oct;49(10):1321-5. PubMed PMID: 11605662.
4. Aoki Y, Ishiwara M, Koda A, Takagaki H. Inhibitory effect of a novel quinolinone derivative, TA-270, on asthmatic inflammatory responses in sensitized guinea pigs. Eur J Pharmacol. 2000 Dec 15;409(3):325-30. PubMed PMID: 11108828.