TAK 029
| Code | Size | Price |
|---|
| TAR-T28913-5mg | 5mg | £1,091.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28913-50mg | 50mg | £2,143.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28913-100mg | 100mg | £2,801.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.
CAS:
176655-58-6
Formula:
C18H21N5O7
Molecular Weight:
419.394
Purity:
0.98
SMILES:
COC(=O)C1N(CCN(CC(O)=O)C1=O)C(=O)CNC(=O)c1ccc(cc1)C(N)=N
References
1. Linneweber J, Dohmen PM, Kertzscher U, Affeld K, Konertz W. Local glycoprotein IIb/IIIa receptor inhibitor delivery from the pump surface attenuates platelet adhesion in continuous flow ventricular assist devices. Artif Organs. 2008 Oct;32(10):792-9. doi: 10.1111/j.1525-1594.2008.00632.x. PubMed PMID: 18959668.
2. Yamamoto J, Yamashita T, Ikarugi H, Taka T, Hashimoto M, Ishii H, Watanabe S, Kovacs IB. G?r?g Thrombosis Test: a global in-vitro test of platelet function and thrombolysis. Blood Coagul Fibrinolysis. 2003 Jan;14(1):31-9. PubMed PMID: 12544726.
3. Tomita Y, Tanahashi N, Tomita M, Itoh Y, Yokoyama M, Takeda H, Schiszler I, Fukuuchi Y. Role of platelet glycoprotein IIb/IIIa in ADP-activated platelet adhesion to aortic endothelial cells in vitro: observation with video-enhanced contrast microscopy. Clin Hemorheol Microcirc. 2001;24(1):1-9. PubMed PMID: 11345228.
4. Kitamura S, Fukushi H, Miyawaki T, Kawamura M, Terashita Z, Sugihara H, Naka T. Novel non-peptide GPIIb/IIIa antagonists: synthesis and biological activities of 2-[4-[2-(4-amidinobenzoylamino)-2-(substituted)acetyl]-3-(2-methoxy-2-oxoethyl)-2 -oxopiperazinyl] acetic acids. Chem Pharm Bull (Tokyo). 2001 Mar;49(3):258-67. PubMed PMID: 11253914.