Teloxantrone HCl

TargetMol
Product Code: TAR-T28944
Supplier: TargetMol
CodeSizePrice
TAR-T28944-5mg5mg£930.00
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Quantity:
TAR-T28944-50mg50mg£1,821.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28944-100mg100mg£2,319.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Teloxantrone, a DNA topoisomerase II inhibitor, is used potentially for the treatment of solid tumors.
CAS:
132937-88-3
Formula:
C21H27Cl2N5O4
Molecular Weight:
484.38
Purity:
0.98
SMILES:
Cl.Cl.CNCCNc1ccc2n(CCNCCO)nc3-c4c(O)ccc(O)c4C(=O)c1c23

References

1. Armand JP. New anticancer drugs in Europe. Gan To Kagaku Ryoho. 1997 May;24 Suppl 1:70-93. Review. PubMed PMID: 9210890. 2. Gogas H, Mansi JL. New drugs. The anthrapyrazoles. Cancer Treat Rev. 1996 Nov;21(6):541-52. Review. PubMed PMID: 8599804. 3. Renner U, Blanz J, Freund S, Waidelich D, Ehninger G, Zeller KP. Biotransformation of CI-937 in primary cultures of rat hepatocytes. Formation of glutathione conjugates. Drug Metab Dispos. 1995 Jan;23(1):94-101. PubMed PMID: 7720531. 4. Raghavan K, Nemeth G, Gray D, Hussain MA. Stabilization of an anthrapyrazole antitumour agent, DuP 937, on complexation with heptakis(2,6-di-O-methyl)-beta-cyclodextrin in aqueous solution. J Pharm Biomed Anal. 1994 Oct;12(10):1259-64. PubMed PMID: 7841220.