Tenofovir disoproxil aspartate
| Code | Size | Price |
|---|
| TAR-T28945-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Tenofovir disoproxil aspartate, a nucleotide reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection.
CAS:
1571075-19-8
Formula:
C23H38N7O13P
Molecular Weight:
651.567
Purity:
0.98
SMILES:
N[C@@H](CC(N)=O)C(O)=O.CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cn1cnc2c(N)ncnc12)OCOC(=O)OC(C)C
References
1. De Clercq E. Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF). Biochem Pharmacol. 2016 Apr 29. pii: S0006-2952(16)30069-7. doi: 10.1016/j.bcp.2016.04.015. [Epub ahead of print] Review. PubMed PMID: 27133890.
2. Mugwanya KK, Baeten JM. Safety of oral tenofovir disoproxil fumarate-based pre-exposure prophylaxis for HIV prevention. Expert Opin Drug Saf. 2016;15(2):265-73. doi: 10.1517/14740338.2016.1128412. Review. PubMed PMID: 26634852; PubMed Central PMCID: PMC4755800.
3. Kabbara WK, Ramadan WH. Emtricitabine/rilpivirine/tenofovir disoproxil fumarate for the treatment of HIV-1 infection in adults. J Infect Public Health. 2015 Sep-Oct;8(5):409-17. doi: 10.1016/j.jiph.2015.04.020. Epub 2015 May 19. Review. PubMed PMID: 26001757.
4. Deeks ED. Emtricitabine/rilpivirine/tenofovir disoproxil fumarate single-tablet regimen: a review of its use in HIV infection. Drugs. 2014 Nov;74(17):2079-95. doi: 10.1007/s40265-014-0318-1. Review. PubMed PMID: 25352394.