Ticolubant
Code | Size | Price |
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TAR-T28974-1mg | 1mg | £239.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28974-5mg | 5mg | £496.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28974-10mg | 10mg | £686.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28974-25mg | 25mg | £1,018.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28974-50mg | 50mg | £1,348.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28974-100mg | 100mg | £1,797.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28974-500mg | 500mg | £3,516.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ticolubant is a leukotriene B4 antagonist.
CAS:
154413-61-3
Formula:
C23H19Cl2NO3S
Molecular Weight:
460.37
Pathway:
Metabolism|Immunology/Inflammation|Membrane transporter/Ion channel
Purity:
0.98
SMILES:
OC(=O)C=Cc1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1
Target:
Calcium Channel|LTR
References
1. Kenny JR, Maggs JL, Tettey JN, Harrell AW, Parker SG, Clarke SE, Park BK. Formation and protein binding of the acyl glucuronide of a leukotriene B4 antagonist (SB-209247): relation to species differences in hepatotoxicity. Drug Metab Dispos. 2005 Feb;33(2):271-81. PubMed PMID: 15523047.
2. Davis HM, Carpenter DC, Stahl JM, Zhang W, Hynicka WP, Griswold DE. Human granulocyte CD11b expression as a pharmacodynamic biomarker of inflammation. J Immunol Methods. 2000 Jun 23;240(1-2):125-32. PubMed PMID: 10854607.
3. Daines RA, Chambers PA, Foley JJ, Griswold DE, Kingsbury WD, Martin LD, Schmidt DB, Sham KK, Sarau HM. (E)-3-[6-[[(2,6-dichlorophenyl)thio]methyl]-3-(2-phenylethoxy)-2- pyridinyl]-2-propenoic acid: a high-affinity leukotriene B4 receptor antagonist with oral antiinflammatory activity. J Med Chem. 1996 Sep 13;39(19):3837-41. PubMed PMID: 8809171.
4. Sarau HM, Foley JJ, Schmidt DB, Tzimas MN, Martin LD, Daines RA, Chambers PA, Kingsbury WD, Griswold DE. SB 209247, a high affinity LTB4 receptor antagonist demonstrating potent antiinflammatory activity. Adv Prostaglandin Thromboxane Leukot Res. 1995;23:275-7. PubMed PMID: 7732852.