Tomopenem
| Code | Size | Price |
|---|
| TAR-T28992-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Tomopenem is a penem antibiotic.
CAS:
222400-20-6
Formula:
C23H35N7O6S
Molecular Weight:
537.64
Purity:
0.98
SMILES:
O=C(C(N12)=C(S[C@@H]3CN(C)[C@H](C(N4C[C@@H](NC(CNC(N)=N)=O)CC4)=O)C3)[C@H](C)[C@]2([H])[C@@H]([C@H](O)C)C1=O)O
References
1. Ansari MA, Shaikh S, Shakil S, Rizvi SM. An enzoinformatics study for prediction of efficacies of three novel penem antibiotics against New Delhi metallo-?-lactamase-1 bacterial enzyme. Interdiscip Sci. 2014 Sep;6(3):208-15. doi: 10.1007/s12539-013-0202-9. PubMed PMID: 25205498.
2. Ansari MA, Shaikh S, Shakil S, Rizvi SM. An enzoinformatics study for prediction of efficacies of three novel penem antibiotics against New Delhi metallo-?-lactamase-1 bacterial enzyme. Interdiscip Sci. 2014 Aug 9. [Epub ahead of print] PubMed PMID: 25118651.
3. Sugihara K, Tateda K, Yamamura N, Koga T, Sugihara C, Yamaguchi K. Efficacy of human-simulated exposures of tomopenem (formerly CS-023) in a murine model of Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus infection. Antimicrob Agents Chemother. 2011 Nov;55(11):5004-9. doi: 10.1128/AAC.00068-11. PubMed PMID: 21844314; PubMed Central PMCID: PMC3195026.
4. Sugihara K, Sugihara C, Matsushita Y, Yamamura N, Uemori M, Tokumitsu A, Inoue H, Kakuta M, Namba E, Nasu H, Koga T. In vivo pharmacodynamic activity of tomopenem (formerly CS-023) against Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus in a murine thigh infection model. Antimicrob Agents Chemother. 2010 Dec;54(12):5298-302. doi: 10.1128/AAC.00267-10. PubMed PMID: 20921311; PubMed Central PMCID: PMC2981229.