Trazium Esilate
| Code | Size | Price |
|---|
| TAR-T29002-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Trazium esilate is an adrenergic receptor antagonist. Trazium esilate is a weak displacer on a1-, a2- and D2-receptors, however, it induced a2-receptor desenzitization after repeated treatment. It had no influence on rat brain cortical noradrenaline and striatal dopamine release evoked by high K+ concentration, but it increased the spontaneous dopamine outflow in rat striatum.
CAS:
97110-59-3
Formula:
C19H18ClN3O4S
Molecular Weight:
419.88
Purity:
0.98
SMILES:
CCS([O-])(=O)=O.OC1(N=CN[n+]2ccc3ccccc3c12)c1ccc(Cl)cc1
References
1. Gyerty?n I, Pet?cz L, Bajn?gel J, Sz?cs Z, Heged?s M, Gy?re K, Gacs?lyi I, Krizs?n D, Fekete MI. Possible involvement of the dopaminergic system in the mode of action of the potential antidepressant trazium esilate. Arzneimittelforschung. 1989 Jul;39(7):775-81. PubMed PMID: 2551306.