TargetMol

UBP141

Product Code:
 
TAR-T29036
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29036-5mg5mg£850.00
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TAR-T29036-50mg50mg£1,661.00
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Quantity:
TAR-T29036-100mg100mg£2,079.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
UBP141 is a antagonist of N-methyl-D-aspartate (NMDA) receptor.
CAS:
344768-30-5
Formula:
C21H18N2O5
Molecular Weight:
378.384
Purity:
0.98
SMILES:
OC(=O)[C@H]1NCCN([C@H]1C(O)=O)C(=O)c1ccc2ccc3ccccc3c2c1

References

1. Yamamoto H, Kamegaya E, Sawada W, Hasegawa R, Yamamoto T, Hagino Y, Takamatsu Y, Imai K, Koga H, Mishina M, Ikeda K. Involvement of the N-methyl-D-aspartate receptor GluN2D subunit in phencyclidine-induced motor impairment, gene expression, and increased Fos immunoreactivity. Mol Brain. 2013 Dec 16;6:56. doi: 10.1186/1756-6606-6-56. PubMed PMID: 24330819; PubMed Central PMCID: PMC3878647. 2. Wang M, Chazot PL, Ali S, Duckett SF, Obrenovitch TP. Effects of NMDA receptor antagonists with different subtype selectivities on retinal spreading depression. Br J Pharmacol. 2012 Jan;165(1):235-44. doi: 10.1111/j.1476-5381.2011.01553.x. PubMed PMID: 21699507; PubMed Central PMCID: PMC3252980. 3. Palygin O, Lalo U, Pankratov Y. Distinct pharmacological and functional properties of NMDA receptors in mouse cortical astrocytes. Br J Pharmacol. 2011 Aug;163(8):1755-66. doi: 10.1111/j.1476-5381.2011.01374.x. PubMed PMID: 21449975; PubMed Central PMCID: PMC3166701. 4. Palygin O, Lalo U, Verkhratsky A, Pankratov Y. Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes. Cell Calcium. 2010 Oct;48(4):225-31. doi: 10.1016/j.ceca.2010.09.004. PubMed PMID: 20926134.