TargetMol

Tanshinone IIA

Product Code:
 
TAR-T2906
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2906-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T2906-20mg20mg£111.00
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Further Information

Bioactivity:
Tanshinone IIA(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.
CAS:
568-72-9
Formula:
C19H18O3
Molecular Weight:
294.35
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9954
SMILES:
Cc1coc-2c1C(=O)C(=O)c1c3CCCC(C)(C)c3ccc-21
Target:
VEGFR

References

1. Fu J, et al. Eur J Pharmacol, 2007, 568(1-3), 213-221. 2. Wang X, et al. Int J Cancer, 2005, 116(5), 799-807. 3. Sun S, et al. Brain Res Bull, 2012, 88(6), 581-588. 4. Ruolin Yang, et al. Med. Chem. Commun., 2014, 5: 1528-1532. 6. Zhang Z, et al. Tanshinone IIA inhibits apoptosis in the myocardium by inducing microRNA-152-3p expression and thereby downregulating PTEN. Am J Transl Res. 2016 Jul 15;8(7):3124-32. 7. Su CC, et al. Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo. Oncol Rep. 2016 Aug;36(2):1173-9.