VUF 8430
| Code | Size | Price |
|---|
| TAR-T29146-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29146-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29146-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
VUF 8430 is a selective agonist for the H4 receptor.
CAS:
98021-17-1
Formula:
C4H11N5S
Molecular Weight:
161.23
Purity:
0.98
SMILES:
NC(N)=NCCSC(N)=N
References
1. Sanna MD, Lucarini L, Durante M, Ghelardini C, Masini E, Galeotti N. Histamine H(4) receptor agonist-induced relief from painful peripheral neuropathy is mediated by inhibition of spinal neuroinflammation and oxidative stress. Br J Pharmacol. 2017 Jan;174(1):28-40. doi: 10.1111/bph.13644. Epub 2016 Nov 18. PubMed PMID: 27714773; PubMed Central PMCID: PMC5341487.
2. Garc?a M, Garc?a-Pedraza J?, Villal?n CM, Mor?n A. Pharmacological Evidence that Histamine H3 Receptors Mediate Histamine-Induced Inhibition of the Vagal Bradycardic Out-flow in Pithed Rats. Basic Clin Pharmacol Toxicol. 2016 Feb;118(2):113-21. doi: 10.1111/bcpt.12475. Epub 2015 Sep 14. PubMed PMID: 26301462.
3. Abiuso AM, Berensztein E, Pagotto RM, Pereyra EN, Medina V, Martinel Lamas DJ, Besio Moreno M, Pignataro OP, Mondillo C. H4 histamine receptors inhibit steroidogenesis and proliferation in Leydig cells. J Endocrinol. 2014 Dec;223(3):241-53. doi: 10.1530/JOE-14-0401. Epub 2014 Sep 24. PubMed PMID: 25253872.
4. Sim YB, Park SH, Kim SS, Kim CH, Kim SJ, Lim SM, Jung JS, Ryu OH, Choi MG, Suh HW. The modulatory role of spinally located histamine receptors in the regulation of the blood glucose level in d-glucose-fed mice. Korean J Physiol Pharmacol. 2014 Feb;18(1):41-6. doi: 10.4196/kjpp.2014.18.1.41. Epub 2014 Feb 13. PubMed PMID: 24634595; PubMed Central PMCID: PMC3951822.