Z060228
| Code | Size | Price |
|---|
| TAR-T29198-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Z060228 is an potent anti-HBV inhibitor. The HBV DNA replication was effectively inhibited by Z060228 in the supernatants of the HepG2.2.15 cells. Z060228 exhibited effects on the self-assembly of Cp149. SEC data revealed that Z060228 altered the equilibrium (a state of stability) of Cp149 assembly.
CAS:
1005459-82-4
Formula:
C20H15ClF4N2O2
Molecular Weight:
426.8
Purity:
0.98
SMILES:
CCOC(=O)C1=C(C)NC(=N[C@H]1c1ccc(F)cc1Cl)c1c(F)cc(F)cc1F
References
1. Guan H, Zhao G, Chen W, Wu G, Liu H, Jiang X, Li S, Wang LL. The novel compound Z060228 inhibits assembly of the HBV capsid. Life Sci. 2015 Jul 15;133:1-7. doi: 10.1016/j.lfs.2015.04.011. Epub 2015 Apr 25. PubMed PMID: 25921762.