ZD-0947
| Code | Size | Price |
|---|
| TAR-T29208-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29208-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29208-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
ZD-0947, a K(ATP) channel activator, is used potentially for the treatment of overactive bladder (OAB).
CAS:
172649-40-0
Formula:
C17H13F3N2O
Molecular Weight:
318.299
Purity:
0.98
SMILES:
FC(F)(F)C1=C[C@H](C2=C(CCCC2=O)N1)c1cccc(c1)C#N
References
1. Mori K, Yamashita Y, Teramoto N. Effects of ZD0947, a novel and potent ATP-sensitive K(+) channel opener, on smooth muscle-type ATP-sensitive K(+) channels. Eur J Pharmacol. 2016 Nov 15;791:773-779. doi: 10.1016/j.ejphar.2016.09.038. PubMed PMID: 27693800.
2. Yunoki T, Zhu HL, Iwasa K, Tomoda T, Aishima M, Shibata A, Naito S, Teramoto N. Comparative studies of ZD0947, a novel ATP-sensitive K(+) channel opener, on guinea pig detrusor and aortic smooth muscles. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jan;376(5):309-19. PubMed PMID: 18071674.
3. Aishima M, Tomoda T, Yunoki T, Nakano T, Seki N, Yonemitsu Y, Sueishi K, Naito S, Ito Y, Teramoto N. Actions of ZD0947, a novel ATP-sensitive K+ channel opener, on membrane currents in human detrusor myocytes. Br J Pharmacol. 2006 Nov;149(5):542-50. PubMed PMID: 17016513; PubMed Central PMCID: PMC2014675.
4. Abdel-Karim AM, Bialecki RA, Elhilali MM. Effects of ZD6169 and ZD0947, 2 potassium adenosine triphosphate channel openers, on bladder function of spinalized rats. J Urol. 2002 Aug;168(2):837-42. PubMed PMID: 12131377.