ZK-95962
| Code | Size | Price |
|---|
| TAR-T29230-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29230-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29230-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
ZK-95962 is an agonist gamma-aminobutyric acid (GABA) receptor. ZK-95962 had selective effects on releasing exploratory locomotor activity suppressed by footshock (punished crossings). ZK-95962 had weak effects on the measures of anxiolytic activity. The feelings of uneasiness and myoclonic jerks, provoked by photostimulation, were also abolished by ZK-95962.
CAS:
101071-43-6
Formula:
C19H22N2O4
Molecular Weight:
342.395
Purity:
0.98
SMILES:
CCOC(=O)c1ncc2[nH]c3cccc(OC(C)C)c3c2c1COC
References
1. Kleven MS, Koek W. Effects of different classes of partial benzodiazepine agonists on punished and unpunished responding in pigeons. Psychopharmacology (Berl). 1999 Jun;144(4):405-10. PubMed PMID: 10435414.
2. Cole BJ, Hillmann M. Effects of benzodiazepine receptor ligands on the performance of an operant delayed matching to position task in rats: opposite effects of FG 7142 and lorazepam. Psychopharmacology (Berl). 1994 Jul;115(3):350-7. PubMed PMID: 7871075.
3. Jones GH, Schneider C, Schneider HH, Seidler J, Cole BJ, Stephens DN. Comparison of several benzodiazepine receptor ligands in two models of anxiolytic activity in the mouse: an analysis based on fractional receptor occupancies. Psychopharmacology (Berl). 1994 Mar;114(2):191-9. PubMed PMID: 7838907.
4. Krause W, Dorow R. Pharmacokinetics of two partial benzodiazepine receptor agonistic beta-carboline derivatives in healthy volunteers. Arzneimittelforschung. 1993 May;43(5):511-5. PubMed PMID: 8392343.