(+)-Carbovir
| Code | Size | Price |
|---|
| TAR-T29244-5mg | 5mg | £1,171.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29244-50mg | 50mg | £2,303.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29244-100mg | 100mg | £3,042.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
(+)-Carbovir is a nucleoside analog with increased chemical stability and increased metabolic stability.
CAS:
124915-24-8
Formula:
C11H13N5O2
Molecular Weight:
247.258
Purity:
0.98
SMILES:
Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@@H](CO)C=C1
References
1. Gautam N, Lin Z, Banoub MG, Smith NA, Maayah A, McMillan J, Gendelman HE, Alnouti Y. Simultaneous quantification of intracellular lamivudine and abacavir triphosphate metabolites by LC-MS/MS. J Pharm Biomed Anal. 2018 May 10;153:248-259. doi: 10.1016/j.jpba.2018.02.036. Epub 2018 Feb 20. PubMed PMID: 29518644; PubMed Central PMCID: PMC5860827.
2. Gao S, Zhu S, Huang R, Li H, Wang H, Zheng G. Engineering the Enantioselectivity and Thermostability of a (+)-?-Lactamase from Microbacterium hydrocarbonoxydans for Kinetic Resolution of Vince Lactam (2-Azabicyclo[2.2.1]hept-5-en-3-one). Appl Environ Microbiol. 2017 Dec 15;84(1). pii: e01780-17. doi: 10.1128/AEM.01780-17. Print 2018 Jan 1. PubMed PMID: 29054871; PubMed Central PMCID: PMC5734046.
3. Gao S, Zhou Y, Zhang W, Wang W, Yu Y, Mu Y, Wang H, Gong X, Zheng G, Feng Y. Structural insights into the ?-lactamase activity and substrate enantioselectivity of an isochorismatase-like hydrolase from Microbacterium hydrocarbonoxydans. Sci Rep. 2017 Mar 15;7:44542. doi: 10.1038/srep44542. PubMed PMID: 28295028; PubMed Central PMCID: PMC5353710.
4. Alvarez A, Rios-Navarro C, Blanch-Ruiz MA, Collado-Diaz V, Andujar I, Martinez-Cuesta MA, Orden S, Esplugues JV. Abacavir induces platelet-endothelium interactions by interfering with purinergic signalling: A step from inflammation to thrombosis. Antiviral Res. 2017 May;141:179-185. doi: 10.1016/j.antiviral.2017.03.001. Epub 2017 Mar 2. PubMed PMID: 28263802.