3'-Chloromethotrexate
Code | Size | Price |
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TAR-T29391-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T29391-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T29391-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
3'-Chloromethotrexate is a chemotherapy agent and immune system suppressant. It can be used to treat cancer, autoimmune diseases, ectopic pregnancy, and medical abortions.
CAS:
5472-96-8
Formula:
C20H21ClN8O5
Molecular Weight:
488.89
Purity:
0.98
SMILES:
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1Cl)C(=O)N[C@@H](CCC(O)=O)C(O)=O
References
1. Rosowsky A, Wright JE, Holden SA, Waxman DJ. Influence of lipophilicity and carboxyl group content on the rate of hydroxylation of methotrexate derivatives by aldehyde oxidase. Biochem Pharmacol. 1990 Aug 15;40(4):851-7. PubMed PMID: 1696821.
2. Klinov SV, Kurganov BI, She?man BM, Gorelik ESh, Birinberg EM. [Inhibition of muscle glycogen phosphorylase b by 5-methyltetrahydrofolic acid, 3'-chloro- and 3',6'-dichloromethotrexates]. Bioorg Khim. 1988 Sep;14(9):1162-5. Russian. PubMed PMID: 3146255.