6-Methylene-4-pregnene-3,20-dione
| Code | Size | Price |
|---|
| TAR-T29475-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
6-Methylene-4-pregnene-3,20-dione has reproductive effect.
CAS:
19457-57-9
Formula:
C22H30O2
Molecular Weight:
326.48
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC(=C)C2=CC(=O)CC[C@]12C
References
1. Roberson KM, Padilla GM, Schmidt JM, Petrow V, Robertson CN. 6-Methylene progesterone is cytotoxic to human cancer cell lines independent of its 5-alpha-reductase activity. Prostate. 1995 Jan;26(1):28-34. PubMed PMID: 7845864.
2. Neubauer BL, Best KL, Blohm TR, Gates C, Goode RL, Hirsch KS, Laughlin ME, Petrow V, Smalstig EB, Stamm NB, et al. LY207320 (6-methylene-4-pregnene-3,20-dione) inhibits testosterone biosynthesis, androgen uptake, 5 alpha-reductase, and produces prostatic regression in male rats. Prostate. 1993;23(3):181-99. PubMed PMID: 8234065.
3. Damber JE, Bergh A, Daehlin L, Petrow V, Landstr?m M. Effects of 6-methylene progesterone on growth, morphology, and blood flow of the Dunning R3327 prostatic adenocarcinoma. Prostate. 1992;20(3):187-97. PubMed PMID: 1574466.
4. Iguchi T, Uesugi Y, Takasugi N, Petrow V. Quantitative analysis of the development of genital organs from the urogenital sinus of the fetal male mouse treated prenatally with a 5 alpha-reductase inhibitor. J Endocrinol. 1991 Mar;128(3):395-401. PubMed PMID: 2013746.