7-Methotrexate
| Code | Size | Price |
|---|
| TAR-T29486-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29486-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29486-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
7-Methotrexate is used as a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and medical abortions.
CAS:
52980-66-2
Formula:
C20H22N8O5
Molecular Weight:
454.447
Purity:
0.98
SMILES:
CN(Cc1cnc2c(N)nc(N)nc2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
References
1. Hung YM, Lin L, Wang YH, Wei JC, Wang PY, Chiou JY. Combination Effect of Anti-Rheumatic Medications for Coronary Artery Diseases Risk in Rheumatoid Arthritis : A Nationwide Population-Based Cohort Study. Curr Med Res Opin. 2018 Jun 25:1-16. doi: 10.1080/03007995.2018.1492910. [Epub ahead of print] PubMed PMID: 29939099.
2. Kesler S, Ogg R, Reddick W, Phillips N, Scoggins M, Glass J, Cheung Y, Pui CH, Robison L, Hudson M, Krull K. Brain network connectivity and executive function in long-term survivors of childhood acute lymphoblastic leukemia. Brain Connect. 2018 Jun 25. doi: 10.1089/brain.2017.0574. [Epub ahead of print] PubMed PMID: 29936880.
3. Sakagami H, Hara Y, Shi H, Iwama S, Nakagawa M, Suzuki H, Tanaka K, Abe T, Tamura N, Takeshima H, Horie N, Kaneko T, Shiratsuchi H, Kaneko T. Change in Anticancer Drug Sensitivity During Neuronal Differentiation of PC12 Cells. In Vivo. 2018 Jul-Aug;32(4):765-770. doi: 10.21873/invivo.11306. PubMed PMID: 29936457.
4. Bitoun S, Nocturne G, Ly B, Krzysiek R, Roques P, Pruvost A, Paoletti A, Pascaud J, D?nnes P, Florence K, Gleizes A, Hincelin-Mery A, Allez M, Hacein-Bey-Abina S, Mackay F, Pallardy M, Le Grand R, Mariette X. Methotrexate and BAFF interaction prevents immunization against TNF inhibitors. Ann Rheum Dis. 2018 Jun 23. pii: annrheumdis-2018-213403. doi: 10.1136/annrheumdis-2018-213403. [Epub ahead of print] PubMed PMID: 29936438.