A61603

TargetMol
Product Code: TAR-T29511
Supplier: TargetMol
CodeSizePrice
TAR-T29511-5mg5mg£930.00
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Quantity:
TAR-T29511-50mg50mg£1,821.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T29511-100mg100mg£2,319.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
A61603 is an alpha-1A adrenergic receptor.
CAS:
750531-54-5
Formula:
C14H19N3O3S
Molecular Weight:
309.38
Purity:
0.98
SMILES:
CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)C1=NCCN1

References

1. Skelly MJ, Ariwodola OJ, Weiner JL. Fear conditioning selectively disrupts noradrenergic facilitation of GABAergic inhibition in the basolateral amygdala. Neuropharmacology. 2017 Feb;113(Pt A):231-240. doi: 10.1016/j.neuropharm.2016.10.003. PubMed PMID: 27720769; PubMed Central PMCID: PMC5148638. 2. Thomas RC, Singh A, Cowley P, Myagmar BE, Montgomery MD, Swigart PM, De Marco T, Baker AJ, Simpson PC. A Myocardial Slice Culture Model Reveals Alpha-1A-Adrenergic Receptor Signaling in the Human Heart. JACC Basic Transl Sci. 2016 Apr;1(3):155-167. PubMed PMID: 27453955; PubMed Central PMCID: PMC4955869. 3. Thomas RC Jr, Cowley PM, Singh A, Myagmar BE, Swigart PM, Baker AJ, Simpson PC. The Alpha-1A Adrenergic Receptor in the Rabbit Heart. PLoS One. 2016 Jun 3;11(6):e0155238. doi: 10.1371/journal.pone.0155238. PubMed PMID: 27258143; PubMed Central PMCID: PMC4892533. 4. Ge D, Yan X, Guo Y, Chen X, Guan R, Chen Y, Qiu D, Wang J. Activation of ?1-adrenoceptors facilitates excitatory inputs to medullary airway vagal preganglionic neurons. J Appl Physiol (1985). 2015 Sep 15;119(6):686-95. doi: 10.1152/japplphysiol.00045.2015. PubMed PMID: 26205539.