ABT-116
| Code | Size | Price |
|---|
| TAR-T29525-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29525-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29525-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
ABT-116 is a transient receptor potential vanillin type 1 antagonist.
CAS:
1008529-42-7
Formula:
C23H27F3N4O
Molecular Weight:
432.491
Purity:
0.98
SMILES:
Cn1ncc2c(NC(=O)NCc3ccc(cc3CCC(C)(C)C)C(F)(F)F)cccc12
References
1. Niyom S, Mama KR, Gustafson DL, Rezende ML. Single- and multiple dose pharmacokinetics and multiple dose pharmacodynamics of oral ABT-116 (a TRPV1 antagonist) in dogs. J Vet Pharmacol Ther. 2015 Aug;38(4):336-43. doi: 10.1111/jvp.12180. Epub 2014 Nov 5. PubMed PMID: 25376244.
2. Malek S, Sample SJ, Schwartz Z, Nemke B, Jacobson PB, Cozzi EM, Schaefer SL, Bleedorn JA, Holzman G, Muir P. Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis. BMC Vet Res. 2012 Oct 4;8:185. doi: 10.1186/1746-6148-8-185. PubMed PMID: 23035739; PubMed Central PMCID: PMC3527270.
3. Niyom S, Mama KR, De Rezende ML. Comparison of the analgesic efficacy of oral ABT-116 administration with that of transmucosal buprenorphine administration in dogs. Am J Vet Res. 2012 Apr;73(4):476-81. doi: 10.2460/ajvr.73.4.476. PubMed PMID: 22452493.
4. Cathcart CJ, Johnston SA, Reynolds LR, Al-Nadaf S, Budsberg SC. Efficacy of ABT-116, an antagonist of transient receptor potential vanilloid type 1, in providing analgesia for dogs with chemically induced synovitis. Am J Vet Res. 2012 Jan;73(1):19-26. doi: 10.2460/ajvr.73.1.19. PubMed PMID: 22204284.