ABT-279
| Code | Size | Price |
|---|
| TAR-T29528-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
ABT-279 is a bio-active chemical.
CAS:
676559-83-4
Formula:
C21H25N5O3
Molecular Weight:
395.463
Purity:
0.98
SMILES:
CC1(CCN(CC1)c1cc(ccn1)C(O)=O)NCC(=O)N1[C@H](CC[C@H]1C#N)C#C
References
1. Gilibili RR, Bhamidipati RK, Mullangi R, Srinivas NR. Retrospective and Prospective Human Intravenous and Oral Pharmacokinetic Projection of Dipeptidyl peptidase-IV Inhibitors Using Simple Allometric Principles - Case Studies of ABT-279, ABT-341, Alogliptin, Carmegliptin, Sitagliptin and Vildagliptin. J Pharm Pharm Sci. 2015;18(3):434-48. PubMed PMID: 26517136.
2. Havale SH, Pal M. Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase-4 for the treatment of type 2 diabetes. Bioorg Med Chem. 2009 Mar 1;17(5):1783-802. doi: 10.1016/j.bmc.2009.01.061. Epub 2009 Jan 31. Review. PubMed PMID: 19217790.
3. Kim J, Flick J, Reimer MT, Rodila R, Wang PG, Zhang J, Ji QC, El-Shourbagy TA. LC-MS/MS determination of 2-(4-((2-(2S,5R)-2-Cyano-5-ethynyl-1-pyrrolidinyl)-2-oxoethylamino)-4-methyl-1-pi peridinyl)-4-pyridinecarboxylic acid (ABT-279) in dog plasma with high-throughput protein precipitation sample preparation. Biomed Chromatogr. 2007 Nov;21(11):1118-26. PubMed PMID: 17590862.
4. Zhang J, Kim EJ, Ji QC, El-Shourbagy TA. Developing multiple high-throughput GLP methods for an investigational drug candidate in various matrices within a 96-well plate. Rapid Commun Mass Spectrom. 2006;20(24):3755-60. PubMed PMID: 17120270