Acetoxycycloheximide
| Code | Size | Price |
|---|
| TAR-T29590-5mg | 5mg | £1,813.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29590-50mg | 50mg | £3,589.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29590-100mg | 100mg | £4,970.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Acetoxycycloheximide induces cell surface TNF receptor 1. It also rapidly induces apoptosis mediated by the release of cytochrome c via activation of c-Jun N-terminal kinase.
CAS:
2885-39-4
Formula:
C17H25NO6
Molecular Weight:
339.388
Purity:
0.98
SMILES:
C[C@H]1C[C@](C)(C[C@@H](C(O)CC2CC(=O)NC(=O)C2)C1=O)OC(C)=O
References
1. Samur DN, Arslan R, Ayd?n S, Bektas N. Valnoctamide: The effect on relieving of neuropathic pain and possible mechanisms. Eur J Pharmacol. 2018 May 15;827:208-214. doi: 10.1016/j.ejphar.2018.03.006. Epub 2018 Mar 6. PubMed PMID: 29522726.
2. Younus I, Reddy DS. A resurging boom in new drugs for epilepsy and brain disorders. Expert Rev Clin Pharmacol. 2018 Jan;11(1):27-45. doi: 10.1080/17512433.2018.1386553. Epub 2017 Oct 23. Review. PubMed PMID: 28956955.
3. Kudin AP, Mawasi H, Eisenkraft A, Elger CE, Bialer M, Kunz WS. Mitochondrial Liver Toxicity of Valproic Acid and Its Acid Derivatives Is Related to Inhibition of α-Lipoamide Dehydrogenase. Int J Mol Sci. 2017 Sep 6;18(9). pii: E1912. doi: 10.3390/ijms18091912. PubMed PMID: 28878165; PubMed Central PMCID: PMC5618561.
4. Ornaghi S, Hsieh LS, Bordey A, Vergani P, Paidas MJ, van den Pol AN. Valnoctamide Inhibits Cytomegalovirus Infection in Developing Brain and Attenuates Neurobehavioral Dysfunctions and Brain Abnormalities. J Neurosci. 2017 Jul 19;37(29):6877-6893. doi: 10.1523/JNEUROSCI.0970-17.2017. Epub 2017 Jun 19. PubMed PMID: 28630251; PubMed Central PMCID: PMC5518418.