TargetMol

Acetylaranotin

Product Code:
 
TAR-T29597
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29597-5mg5mg£3,018.00
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TAR-T29597-50mg50mg£5,998.00
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Quantity:
TAR-T29597-100mg100mg£8,584.00
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This product comes from: United States.
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Further Information

Bioactivity:
Acetylaranotin belongs to one structural subgroup of ETPs characterized by the presence of a seven-membered 4,5-dihydrooxepine ring.
CAS:
20485-01-2
Formula:
C22H20N2O8S2
Molecular Weight:
504.53
Purity:
0.98
SMILES:
CC(=O)O[C@H]1C=COC=C2C[C@@]34SS[C@]5(CC6=COC=C[C@H](OC(C)=O)[C@@H]6N5C3=O)C(=O)N4[C@@H]12

References

1. Guo CJ, Yeh HH, Chiang YM, Sanchez JF, Chang SL, Bruno KS, Wang CC. Biosynthetic pathway for the epipolythiodioxopiperazine acetylaranotin in Aspergillus terreus revealed by genome-based deletion analysis. J Am Chem Soc. 2013 May 15;135(19):7205-13. doi: 10.1021/ja3123653. Epub 2013 May 1. PubMed PMID: 23586797; PubMed Central PMCID: PMC3695726. 2. Fujiwara H, Kurogi T, Okaya S, Okano K, Tokuyama H. Total synthesis of (-)-acetylaranotin. Angew Chem Int Ed Engl. 2012 Dec 21;51(52):13062-5. doi: 10.1002/anie.201207307. Epub 2012 Nov 19. PubMed PMID: 23161829. 3. Belov DS, Ratmanova NK, Andreev IA, Kurkin AV. Synthesis of bicyclic proline derivatives by the aza-Cope-Mannich reaction: formal synthesis of (?)-acetylaranotin. Chemistry. 2015 Mar 2;21(10):4141-7. doi: 10.1002/chem.201405811. Epub 2015 Jan 28. PubMed PMID: 25631763. 4. Codelli JA, Puchlopek AL, Reisman SE. Enantioselective total synthesis of (-)-acetylaranotin, a dihydrooxepine epidithiodiketopiperazine. J Am Chem Soc. 2012 Feb 1;134(4):1930-3. doi: 10.1021/ja209354e. Epub 2011 Oct 28. PubMed PMID: 22023250; PubMed Central PMCID: PMC3271125.