AD 5467
| Code | Size | Price |
|---|
| TAR-T29634-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
AD-5467 is a bioactive chemical.
CAS:
138333-32-1
Formula:
C16H21NO3S
Molecular Weight:
307.41
Purity:
0.98
SMILES:
CC(C)C1Oc2c(cccc2N(CC(O)=O)C1=S)C(C)C
References
1. Win T, Asano G, Shimizu Y. The efficacy of aldose reductase inhibitor, antioxidant butylated hydroxytoluene and cysteine protease inhibitor E64 on hyperglycemia-induced metabolic changes in the organ-cultured bovine lens. Nihon Ika Daigaku Zasshi. 1994 Jun;61(3):180-9. PubMed PMID: 8045992.
2. Chanalet L, Lapalus P. Drugs designed to maintain the transparence of the ocular lens. Fundam Clin Pharmacol. 1994;8(4):322-41. Review. PubMed PMID: 7851838.
3. Ohtori A, Yamamoto Y, Tojo KJ. Penetration and binding of aldose-reductase inhibitors in the lens. Invest Ophthalmol Vis Sci. 1991 Jan;32(1):189-93. PubMed PMID: 1898917.
4. Tawada H, Sugiyama Y, Ikeda H, Yamamoto Y, Meguro K. Studies on antidiabetic agents. IX. A new aldose reductase inhibitor, AD-5467, and related 1,4-benzoxazine and 1,4-benzothiazine derivatives: synthesis and biological activity. Chem Pharm Bull (Tokyo). 1990 May;38(5):1238-45. PubMed PMID: 2118427.