Aerobactin
| Code | Size | Price |
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| TAR-T29677-5mg | 5mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Aerobactin, as a bacterial iron chelating agent (siderophore), can be found in E. coli. It is a virulence factor that can enable E. coli to sequester iron in iron-poor environments.
CAS:
26198-65-2
Formula:
C22H36N4O13
Molecular Weight:
564.545
Purity:
0.98
SMILES:
CC(=O)N(O)CCCC[C@H](NC(=O)CC(O)(CC(=O)N[C@@H](CCCCN(O)C(C)=O)C(O)=O)C(O)=O)C(O)=O
References
1. Micenkov? L, Frankovi?ov? L, Jaborn?kov? I, Bos?k J, D?t? P, ?marda J, Vrba M, ?ev??kov? A, Kme?ov? M, ?majs D. Escherichia coli isolates from patients with inflammatory bowel disease: ExPEC virulence- and colicin-determinants are more frequent compared to healthy controls. Int J Med Microbiol. 2018 May 1. pii: S1438-4221(17)30516-7. doi: 10.1016/j.ijmm.2018.04.008. [Epub ahead of print] PubMed PMID: 29735381.
2. Song T, Liu H, Lv T, Zhao X, Shao Y, Han Q, Li C, Zhang W. Characteristics of the iron uptake-related process of a pathogenic Vibrio splendidus strain associated with massive mortalities of the sea cucumber Apostichopus japonicus. J Invertebr Pathol. 2018 May 4;155:25-31. doi: 10.1016/j.jip.2018.05.001. [Epub ahead of print] PubMed PMID: 29729885.
3. Bailey DC, Alexander E, Rice MR, Drake EJ, Mydy LS, Aldrich CC, Gulick AM. Structural and functional delineation of aerobactin biosynthesis in hypervirulent Klebsiella pneumoniae. J Biol Chem. 2018 May 18;293(20):7841-7852. doi: 10.1074/jbc.RA118.002798. Epub 2018 Apr 4. PubMed PMID: 29618511; PubMed Central PMCID: PMC5961048.
4. Thode SK, Rojek E, Kozlowski M, Ahmad R, Haugen P. Distribution of siderophore gene systems on a Vibrionaceae phylogeny: Database searches, phylogenetic analyses and evolutionary perspectives. PLoS One. 2018 Feb 14;13(2):e0191860. doi: 10.1371/journal.pone.0191860. eCollection 2018. PubMed PMID: 29444108; PubMed Central PMCID: PMC5812596.