AG 127

TargetMol
Product Code: TAR-T29696
Supplier: TargetMol
CodeSizePrice
TAR-T29696-5mg5mg£850.00
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Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
AG 127 is a biochemical.
CAS:
90947-89-0
Formula:
C10H5N3O3
Molecular Weight:
215.168
Purity:
0.98
SMILES:
Oc1ccc(C=C(C#N)C#N)cc1[N+]([O-])=O

References

1. Menzfeld C, John M, van Rossum D, Regen T, Scheffel J, Janova H, G?tz A, Ribes S, Nau R, Borisch A, Boutin P, Neumann K, Bremes V, Wienands J, Reichardt HM, L?hder F, Tischner D, Waetzig V, Herdegen T, Teismann P, Greig I, M?ller M, Pukrop T, Mildner A, Kettenmann H, Br?ck W, Prinz M, Rotshenker S, Weber MS, Hanisch UK. Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism. Glia. 2015 Jun;63(6):1083-99. doi: 10.1002/glia.22803. Epub 2015 Mar 2. PubMed PMID: 25731696. 2. Voss K, Amaya M, Mueller C, Roberts B, Kehn-Hall K, Bailey C, Petricoin E 3rd, Narayanan A. Inhibition of host extracellular signal-regulated kinase (ERK) activation decreases new world alphavirus multiplication in infected cells. Virology. 2014 Nov;468-470:490-503. doi: 10.1016/j.virol.2014.09.005. Epub 2014 Sep 27. PubMed PMID: 25261871. 3. Koss DJ, Riedel G, Bence K, Platt B. Store-operated Ca2+ entry in hippocampal neurons: Regulation by protein tyrosine phosphatase PTP1B. Cell Calcium. 2013 Feb;53(2):125-38. doi: 10.1016/j.ceca.2012.11.004. Epub 2012 Dec 4. PubMed PMID: 23218930. 4. Turpaev K, Ermolenko M, Cresteil T, Drapier JC. Benzylidenemalononitrile compounds as activators of cell resistance to oxidative stress and modulators of multiple signaling pathways. A structure-activity relationship study. Biochem Pharmacol. 2011 Sep 1;82(5):535-47. doi: 10.1016/j.bcp.2011.05.028. Epub 2011 Jun 2. PubMed PMID: 21669191.