Agosterol A
| Code | Size | Price |
|---|
| TAR-T29729-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Agosterol A is isolated from marine sponge Spongia.
CAS:
213549-32-7
Formula:
C33H52O8
Molecular Weight:
576.771
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H]([C@H](C)[C@H](O)CCC(C)C)[C@@]1(C)C[C@@H](O)[C@@]1([H])C2=C[C@H](OC(C)=O)[C@@]2([H])[C@@H](OC(C)=O)[C@H](CC[C@]12C)OC(C)=O
References
1. Abraham I, El Sayed K, Chen ZS, Guo H. Current status on marine products with reversal effect on cancer multidrug resistance. Mar Drugs. 2012 Oct;10(10):2312-21. doi: 10.3390/md10102312. Epub 2012 Oct 19. Review. PubMed PMID: 23170086; PubMed Central PMCID: PMC3497025.
2. Ren XQ, Furukawa T, Yamamoto M, Aoki S, Kobayashi M, Nakagawa M, Akiyama S. A functional role of intracellular loops of human multidrug resistance protein 1. J Biochem. 2006 Sep;140(3):313-8. Epub 2006 Jul 21. PubMed PMID: 16861249.
3. Noguchi T, Ren XQ, Aoki S, Igarashi Y, Che XF, Nakajima Y, Takahashi H, Mitsuo R, Tsujikawa K, Sumizawa T, Haraguchi M, Kobayashi M, Goto S, Kanehisa M, Aikou T, Akiyama S, Furukawa T. MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (beta-D-glucuronate). Biochem Pharmacol. 2005 Oct 1;70(7):1056-65. PubMed PMID: 16098482.
4. Ren XQ, Furukawa T, Nakajima Y, Takahashi H, Aoki S, Sumizawa T, Haraguchi M, Kobayashi M, Chijiiwa K, Akiyama S. GSH inhibits trypsinization of the C-terminal half of human MRP1. J Biol Chem. 2005 Feb 18;280(7):6231-7. Epub 2004 Dec 3. PubMed PMID: 15579473.