Ahc 52
| Code | Size | Price |
|---|
| TAR-T29743-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ahc 52 is a biochemical.
CAS:
119666-09-0
Formula:
C30H36N4O4
Molecular Weight:
516.642
Purity:
0.98
SMILES:
COC(=O)C1=C(C)NC(C)=C(C1c1c(nn2ccccc12)C(C)C)C(=O)OCCN(C)Cc1ccccc1
References
1. Yamashiro T, Watanabe N, Yokoyama KK, Koga C, Tsuruo T, Kobayashi Y. Requirement of expression of P-glycoprotein on human natural killer leukemia cells for cell-mediated cytotoxicity. Biochem Pharmacol. 1998 May 1;55(9):1385-90. PubMed PMID: 10076529.
2. Tanaka H, Sekine T, Terada M, Kobayashi Y, Shigenobu K. Cardioprotective effect against ischemia-reperfusion injury of AHC-52, a dihydropyridine compound with inhibitory effect on Cl- but not Ca2+ current. Naunyn Schmiedebergs Arch Pharmacol. 1997 Dec;356(6):853-5. PubMed PMID: 9453474.
3. Yamashiro T, Watanabe N, Kobayashi Y. Reduction of intracellular pH by inhibitors of natural killer cell activity, nicardipine, methyl 2-(N-benzyl-N-methylamino)ethyl-2,6-dimethyl-4-(2-isopropyl-pyrazolo[1, 5-a]pyridine-3-yl)-1,4-dihydro-pyridine-3,5-dicarboxylate (AHC-52), and 4,4'-diisothiocyano-2,2'-disulfonic acid stilbene (DIDS). Biochem Pharmacol. 1997 Jul 1;54(1):143-8. PubMed PMID: 9296360.
4. Yao Y, Sei Y, Abbracchio MP, Jiang JL, Kim YC, Jacobson KA. Adenosine A3 receptor agonists protect HL-60 and U-937 cells from apoptosis induced by A3 antagonists. Biochem Biophys Res Commun. 1997 Mar 17;232(2):317-22. PubMed PMID: 9125172; PubMed Central PMCID: PMC4309999.