Alatrofloxacin Mesylate
Code | Size | Price |
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TAR-T29829-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Alatrofloxacin Mesylate is the parental prodrug of broad-spectrum antibiotic trovafloxacin.
CAS:
157605-25-9
Formula:
C27H29F3N6O8S
Molecular Weight:
654.62
Purity:
0.98
SMILES:
CS(O)(=O)=O.[H][C@@]12CN(C[C@]1([H])C2NC(=O)[C@H](C)NC(=O)[C@H](C)N)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F
References
1. Mukherjee J. Post-approval translational research itself has diverse ethics. Am J Bioeth. 2010 Aug;10(8):43-4. doi: 10.1080/15265161.2010.496525. PubMed PMID: 20694908.
2. Hsiao CJ, Younis H, Boelsterli UA. Trovafloxacin, a fluoroquinolone antibiotic with hepatotoxic potential, causes mitochondrial peroxynitrite stress in a mouse model of underlying mitochondrial dysfunction. Chem Biol Interact. 2010 Oct 6;188(1):204-13. doi: 10.1016/j.cbi.2010.07.017. Epub 2010 Jul 23. PubMed PMID: 20655887.
3. Annas GJ. Globalized clinical trials and informed consent. N Engl J Med. 2009 May 14;360(20):2050-3. doi: 10.1056/NEJMp0901474. PubMed PMID: 19439740.
4. Ezeome ER, Simon C. Ethical problems in conducting research in acute epidemics: the Pfizer meningitis study in Nigeria as an illustration. Dev World Bioeth. 2010 Apr;10(1):1-10. doi: 10.1111/j.1471-8847.2008.00239.x. Epub 2008 Jul 28. PubMed PMID: 18665846.