ALK-001
| Code | Size | Price |
|---|
| TAR-T29867-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
ALK-001 is a vitamin A analog, which may be used to treat Stargardt disease.
CAS:
118139-36-9
Formula:
C22H32O2
Molecular Weight:
331.514
Purity:
0.98
SMILES:
[2H]C([2H])([2H])C(=C/COC(C)=O)C=CC=C(/C)C=CC1=C(C)CCCC1(C)C
References
1. Saad L, Washington I. Can Vitamin A be Improved to Prevent Blindness due to Age-Related Macular Degeneration, Stargardt Disease and Other Retinal Dystrophies? Adv Exp Med Biol. 2016;854:355-61. doi: 10.1007/978-3-319-17121-0_47. PubMed PMID: 26427432.
2. Charbel Issa P, Barnard AR, Herrmann P, Washington I, MacLaren RE. Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8415-20. doi: 10.1073/pnas.1506960112. PubMed PMID: 26106163; PubMed Central PMCID: PMC4500285.