Altropane
| Code | Size | Price |
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| TAR-T29920-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Altropane is a SPECT imaging agent used for viewing dopamine transporter sites.
CAS:
180468-34-2
Formula:
C18H21FINO2
Molecular Weight:
429.274
Purity:
0.98
SMILES:
[H][C@]12CC[C@]([H])([C@H]([C@H](C1)c1ccc(F)cc1)C(=O)OC)N2CC=CI
References
1. Gleave JA, Farncombe TH, Saab C, Doering LC. Correlative single photon emission computed tomography imaging of [123I]altropane binding in the rat model of Parkinson's. Nucl Med Biol. 2011 Jul;38(5):741-9. doi: 10.1016/j.nucmedbio.2010.12.006. Epub 2011 Mar 30. PubMed PMID: 21718949.
2. Fang YH, El Fakhri G, Becker JA, Alpert NM. Parametric imaging with Bayesian priors: a validation study with (11)C-Altropane PET. Neuroimage. 2012 May 15;61(1):131-8. doi: 10.1016/j.neuroimage.2012.03.003. Epub 2012 Mar 9. PubMed PMID: 22425668.
3. Marquie M, Locascio JJ, Rentz DM, Becker JA, Hedden T, Johnson KA, Growdon JH, Gomperts SN. Striatal and extrastriatal dopamine transporter levels relate to cognition in Lewy body diseases: an (11)C altropane positron emission tomography study. Alzheimers Res Ther. 2014 Aug 27;6(5-8):52. doi: 10.1186/s13195-014-0052-7. eCollection 2014. PubMed PMID: 25429309; PubMed Central PMCID: PMC4245149.
4. Spencer TJ, Bonab AA, Dougherty DD, Mirto T, Martin J, Clarke A, Fischman AJ. Understanding the central pharmacokinetics of spheroidal oral drug absorption system (SODAS) dexmethylphenidate: a positron emission tomography study of dopamine transporter receptor occupancy measured with C-11 altropane. J Clin Psychiatry. 2012 Mar;73(3):346-52. doi: 10.4088/JCP.10m06393. Epub 2011 Nov 1. PubMed PMID: 22154896.