AM-3102

TargetMol
Product Code: TAR-T29938
Supplier: TargetMol
CodeSizePrice
TAR-T29938-5mg5mg£850.00
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Quantity:
TAR-T29938-50mg50mg£1,661.00
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Quantity:
TAR-T29938-100mg100mg£2,079.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.
CAS:
213182-22-0
Formula:
C21H41NO2
Molecular Weight:
339.564
Purity:
0.98
SMILES:
CCCCCCCCC=C/CCCCCCCC(=O)N[C@H](C)CO

References

1. Orio L, Alen F, Pav?n FJ, Serrano A, Garc?a-Bueno B. Oleoylethanolamide, Neuroinflammation, and Alcohol Abuse. Front Mol Neurosci. 2019 Jan 9;11:490. doi: 10.3389/fnmol.2018.00490. eCollection 2018. Review. PubMed PMID: 30687006; PubMed Central PMCID: PMC6333756. 2. Bowen KJ, Kris-Etherton PM, Shearer GC, West SG, Reddivari L, Jones PJH. Oleic acid-derived oleoylethanolamide: A nutritional science perspective. Prog Lipid Res. 2017 Jul;67:1-15. doi: 10.1016/j.plipres.2017.04.001. Epub 2017 Apr 5. Review. PubMed PMID: 28389247. 3. Brown JD, Karimian Azari E, Ayala JE. Oleoylethanolamide: A fat ally in the fight against obesity. Physiol Behav. 2017 Jul 1;176:50-58. doi: 10.1016/j.physbeh.2017.02.034. Epub 2017 Feb 27. Review. PubMed PMID: 28254531. 4. Zhou H, Yang WS, Li Y, Ren T, Peng L, Guo H, Liu JF, Zhou Y, Zhao Y, Yang LC, Jin X. Oleoylethanolamide attenuates apoptosis by inhibiting the TLR4/NF-?B and ERK1/2 signaling pathways in mice with acute ischemic stroke. Naunyn Schmiedebergs Arch Pharmacol. 2017 Jan;390(1):77-84. doi: 10.1007/s00210-016-1309-4. Epub 2016 Oct 13. PubMed PMID: 27738712.