AMG-126737
| Code | Size | Price |
|---|
| TAR-T29969-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
AMG-126737 is an effective human lung mast cell trypsin inhibitor with potential therapeutic effect in lung diseases.
CAS:
224054-76-6
Formula:
C33H38N6O6S2
Molecular Weight:
678.82
Purity:
0.98
SMILES:
NC(=N)c1cccc(c1)S(=O)(=O)NCc1ccc(OCCCCCOc2ccc(CNS(=O)(=O)c3cccc(c3)C(N)=N)cc2)cc1
References
1. Wright CD, Havill AM, Middleton SC, Kashem MA, Dripps DJ, Abraham WM, Thomson DS, Burgess LE. Inhibition of allergen-induced pulmonary responses by the selective tryptase inhibitor 1,5-bis-[4-[(3-carbamimidoyl-benzenesulfonylamino)-methyl]-phenoxy]-pen tane (AMG-126737). Biochem Pharmacol. 1999 Dec 15;58(12):1989-96. PubMed PMID: 10591155.