TargetMol

Ganoderenic acid B

Product Code:
 
TAR-T2S1120
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T2S1120-50mg50mgEnquire
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TAR-T2S1120-1mg1mg£198.00
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TAR-T2S1120-5mg5mg£389.00
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TAR-T2S1120-1mL1 mL * 10 mM (in DMSO)£464.00
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TAR-T2S1120-10mg10mg£547.00
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TAR-T2S1120-25mg25mg£817.00
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Further Information

Bioactivity:
Ganoderenic acid B can enhance the cytotoxicity of chemotherapeutics towards ABCB1-mediated MDR cancer cells via inhibition of the transport function of ABCB1.
CAS:
100665-41-6
Formula:
C30H42O7
Molecular Weight:
514.65
Pathway:
Membrane transporter/Ion channel|Neuroscience
Purity:
0.98
SMILES:
CC(CC(=O)C=C(/C)[C@H]1CC(=O)[C@@]2(C)C3=C(C(=O)C[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1C[C@@H]3O)C(O)=O
Target:
P-gp

References

Liu DL, et al. Ganoderma lucidum derived ganoderenic acid B reverses ABCB1-mediated multidrug resistance in HepG2/ADM cells. Int J Oncol. 2015;46(5):2029-2038.