ASS234
Code | Size | Price |
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TAR-T30176-5mg | 5mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30176-50mg | 50mg | £1,982.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30176-100mg | 100mg | £2,560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.
CAS:
1334106-34-1
Formula:
C29H37N3O
Molecular Weight:
443.635
Purity:
0.98
SMILES:
CN(CC#C)Cc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2n1C
References
1. Serrano MP, Herrero-Labrador R, Futch HS, Serrano J, Romero A, Fernandez AP, Samadi A, Unzeta M, Marco-Contelles J, Mart?nez-Murillo R. The proof-of-concept of ASS234: Peripherally administered ASS234 enters the central nervous system and reduces pathology in a male mouse model of Alzheimer disease. J Psychiatry Neurosci. 2016 Sep 20;41(6):150209. doi: 10.1503/jpn.150209. [Epub ahead of print] PubMed PMID: 27636528.
2. Ramsay RR, Majekova M, Medina M, Valoti M. Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration. Front Neurosci. 2016 Aug 22;10:375. doi: 10.3389/fnins.2016.00375. Review. PubMed PMID: 27597816; PubMed Central PMCID: PMC4992697.
3. Marco-Contelles J, Unzeta M, Bolea I, Esteban G, Ramsay RR, Romero A, Mart?nez-Murillo R, Carreiras MC, Ismaili L. ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy. Front Neurosci. 2016 Jun 28;10:294. doi: 10.3389/fnins.2016.00294. PubMed PMID: 27445665; PubMed Central PMCID: PMC4923252.
4. Ramos E, Romero A, Marco-Contelles J, Del Pino J. Upregulation of Antioxidant Enzymes by ASS234, a Multitarget Directed Propargylamine for Alzheimer's Disease Therapy. CNS Neurosci Ther. 2016 Sep;22(9):799-802. doi: 10.1111/cns.12590. PubMed PMID: 27380946.