AWD 12-281
Code | Size | Price |
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TAR-T30232-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30232-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30232-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
AWD 12-281 is a selective phosphodiesterase 4 (PDE4) inhibitor used for the treatment of pulmonary inflammation by inhalation.
CAS:
257892-33-4
Formula:
C22H14Cl2FN3O3
Molecular Weight:
458.27
Purity:
0.98
SMILES:
Oc1ccc2n(Cc3ccc(F)cc3)cc(C(=O)C(=O)Nc3c(Cl)cncc3Cl)c2c1
References
1. Hoppmann J, B?umer W, Galetzka C, H?fgen N, Kietzmann M, Rundfeldt C. The phosphodiesterase 4 inhibitor AWD 12-281 is active in a new guinea-pig model of allergic skin inflammation predictive of human skin penetration and suppresses both Th1 and Th2 cytokines in mice. J Pharm Pharmacol. 2005 Dec;57(12):1609-17. PubMed PMID: 16354405.