ML-7 hydrochloride
Code | Size | Price |
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TAR-T3050-5mg | 5mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3050-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3050-10mg | 10mg | £125.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3050-25mg | 25mg | £193.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3050-50mg | 50mg | £300.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3050-100mg | 100mg | £368.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3050-200mg | 200mg | £458.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
ML-7 Hcl is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-muscle myosin light chain kinase, PKA, and PKC.
CAS:
110448-33-4
Formula:
C15H18ClIN2O2S
Molecular Weight:
452.74
Pathway:
Cytoskeletal Signaling; Stem Cells; Metabolism; Tyrosine Kinase/Adaptors; Chromatin/Epigenetic; Cell Cycle/Checkpoint
Purity:
0.9961
SMILES:
C1CNCCN(C1)S(=O)(=O)c1cccc2c1cccc2I.Cl
Target:
Serine/threonin kinase; Myosin; YAP; PKA; PKC
References
1. Cheng X, et al. Mol Med Rep. 2015, 12(3):4109-16.
2. Connell LE, et al. J Cell Sci. 2006, 119(Pt 11):2269-81.
3. Saitoh M, et al. J Biol Chem. 1987, 262(16):7796-801.
4. Fazal F, et al. Mol Cell Biol. 2005, 25(14):6259-66.
5. Zhang H, Lin F, Huang J, et al. Anisotropic stiffness gradient-regulated mechanical guidance drives directional migration of cancer cells[J]. Acta Biomaterialia. 2020.