BMS-247243
| Code | Size | Price |
|---|
| TAR-T30509-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
BMS-247243 is a novel cephalosporin inhibitor that is mainly active against Gram-positive bacteria and also against methicillin-resistant Staphylococcus.
CAS:
307316-55-8
Formula:
C36H41Cl2N5O8S3
Molecular Weight:
838.83
Purity:
0.98
SMILES:
Cc1cc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)CSc2cc(Cl)c(C=CC(=O)NCC([O-])=O)cc2Cl)C3=O)C([O-])=O)cc(C)[n+]1CCC[N+]1(C)CCOCC1
References
1. Shahid M, Sobia F, Singh A, Malik A, Khan HM, Jonas D, Hawkey PM. Beta-lactams and beta-lactamase-inhibitors in current- or potential-clinical practice: a comprehensive update. Crit Rev Microbiol. 2009;35(2):81-108. doi: 10.1080/10408410902733979. Review. PubMed PMID: 19514910.
2. Clark J, Fung-Tomc JC, Minassian B, Tsai YH, Yang H, Huczko E, Kolek B, Chaniewski S, Ferraro C, Drain R, Gradelski E, Bonner DP. In vitro and in vivo activities of a novel cephalosporin, BMS-247243, against organisms other than staphylococci. Antimicrob Agents Chemother. 2002 Apr;46(4):1108-11. PubMed PMID: 11897599; PubMed Central PMCID: PMC127083.
3. Fung-Tomc JC, Clark J, Minassian B, Pucci M, Tsai YH, Gradelski E, Lamb L, Medina I, Huczko E, Kolek B, Chaniewski S, Ferraro C, Washo T, Bonner DP. In vitro and in vivo activities of a novel cephalosporin, BMS-247243, against methicillin-resistant and -susceptible staphylococci. Antimicrob Agents Chemother. 2002 Apr;46(4):971-6. PubMed PMID: 11897577; PubMed Central PMCID: PMC127082.
4. Johnson AP. Anti-MRSA cephalosporins Bristol-Myers Squibb. Curr Opin Investig Drugs. 2001 Feb;2(2):205-8. Review. PubMed PMID: 11816831.