BQ 485
Code | Size | Price |
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TAR-T30572-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30572-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30572-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
BQ 484 is an endothelin (ET) receptor antagonist.
CAS:
141594-26-5
Formula:
C35H44N6O5
Molecular Weight:
628.774
Purity:
0.98
SMILES:
CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O
References
1. Sakuma I, Asajima H, Fukao M, Tohse N, Tamura M, Kitabatake A. Effects of BQ-485, a selective ETA antagonist, on endothelin-mediated vasomotion in rat coronary vascular beds. J Cardiovasc Pharmacol. 1995;26 Suppl 3:S400-3. PubMed PMID: 8587427.
2. Takasu A, Matsushima S, Takino M, Okada Y. Effect of an endothelin-1 antagonist, BQ-485, on cerebral oxygen metabolism after complete global cerebral ischemia in dogs. Resuscitation. 1997 Feb;34(1):65-9. PubMed PMID: 9051826.
3. Itoh S, Sasaki T, Ide K, Ishikawa K, Nishikibe M, Yano M. A novel endothelin ETA receptor antagonist, BQ-485, and its preventive effect on experimental cerebral vasospasm in dogs. Biochem Biophys Res Commun. 1993 Sep 15;195(2):969-75. PubMed PMID: 8373429.
4. Holl? G, K?thy P, Lakatos P, Vargha P. Endothelin-A receptor antagonist BQ-485 protects against intraocular pressure spike induced by laser trabeculoplasty in the rabbit. Ophthalmologica. 2002 Nov-Dec;216(6):459-62. PubMed PMID: 12566893.