(Z)-SMI-4a

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TargetMol
Product Code: TAR-T3058
Supplier: TargetMol
CodeSizePrice
TAR-T3058-1mL1 mL * 10 mM (in DMSO)£108.00
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TAR-T3058-5mg5mg£108.00
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TAR-T3058-10mg10mg£124.00
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TAR-T3058-25mg25mg£189.00
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TAR-T3058-50mg50mg£254.00
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TAR-T3058-100mg100mg£344.00
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TAR-T3058-200mg200mg£483.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
(Z)-SMI-4a is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.
CAS:
438190-29-5
Formula:
C11H6F3NO2S
Molecular Weight:
273.23
Pathway:
Chromatin/Epigenetic; JAK/STAT signaling
Purity:
0.9944
SMILES:
FC(F)(F)c1cccc(C=C2/SC(=O)NC2=O)c1
Target:
Pim

References

1. Beharry Z, et al. Mol Cancer Ther, 2009, 8(6), 1473-1483. 2. Lin YW, et al. Blood, 2010, 115(4), 824-833.