Bufotoxin
| Code | Size | Price |
|---|
| TAR-T30610-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Bufotoxin, a toxic steroid lactone, exists in the parotoid glands, skin, and poison of many toads and other amphibians, and in some plants and mushrooms.
CAS:
464-81-3
Formula:
C40H60N4O10
Molecular Weight:
756.938
Purity:
0.98
SMILES:
CC(=O)O[C@H]1C[C@]2(O)[C@@H]3CC[C@@H]4C[C@H](CC[C@]4(C)[C@H]3CC[C@]2(C)[C@H]1c1ccc(=O)oc1)OC(=O)CCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O
References
1. Ashok G, Ramkumar, Sakunthala SR, Rajasekaran D. An interesting case of cardiotoxicity due to bufotoxin (toad toxin). J Assoc Physicians India. 2011 Nov;59:737-8. PubMed PMID: 22616345.
2. Shimada K, Nambara T. Isolation and characterization of a new type of bufotoxin from the skin of Bufo americanus. Chem Pharm Bull (Tokyo). 1980 May;28(5):1559-62. PubMed PMID: 7408047.
3. ARORA RB. Studies on veratrum alkaloids. XVII. The antiveratrinic action of the cardiac glycosides and of bufotoxin. J Pharmacol Exp Ther. 1953 May;108(1):26-32. PubMed PMID: 13053418.
4. Meng Q, Yau LF, Lu JG, Wu ZZ, Zhang BX, Wang JR, Jiang ZH. Chemical profiling and cytotoxicity assay of bufadienolides in toad venom and toad skin. J Ethnopharmacol. 2016 Jul 1;187:74-82. doi: 10.1016/j.jep.2016.03.062. Epub 2016 Apr 6. PubMed PMID: 27063985.