C012 Dihydrochloride
Code | Size | Price |
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TAR-T30676-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30676-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30676-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
C012 Dihydrochloride is a novel small molecule compound that sensitized BRAF wild-type melanoma cells to verofenib. It can significantly reduce the activity of melanoma cells and has limited toxicity to normal human fibroblasts.
CAS:
1219163-50-4
Formula:
C23H30Cl2N4O
Molecular Weight:
449.42
Purity:
0.98
SMILES:
Cl.Cl.CCOc1ccc(cc1)-c1cn2c(n1)n(CCN(CC)CC)c1ccccc21
References
1. Sutton SK, Carter DR, Kim P, et al. A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner. Oncotarget. 2016;7(32):52166-52178. doi:10.18632/oncotarget.10700.