Cgp 43182
| Code | Size | Price |
|---|
| TAR-T30831-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T30831-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T30831-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
CGP 43182 is an effective inhibitor of group IIA secretory phospholipase A2 (Group IIA sPLA2) activity in vitro, which can be used to prevent the synergistic effect of pro-inflammatory genes stimulated by cytokines mediated by NFkappaB.
CAS:
150379-37-6
Formula:
C16H15Cl2NO5
Molecular Weight:
372.2
Purity:
0.98
SMILES:
OC1=C(C(=O)Nc2cccc(Cl)c2Cl)C(=O)OC2(CCCCC2)O1
References
1. Kumar KN, Johnson PS, Chen X, Pal R, Ahmad M, Ragland T, Bigge C, Michaelis EK. Cloning of a brain N-methyl-D-aspartate- and D, L-epsilon-2-amino-4-propyl-5-phosphono-3-pentanoic acid (CGP 39653)-binding protein. Biochem Biophys Res Commun. 1998 Dec 18;253(2):463-9. PubMed PMID: 9878559.
2. Mugnaini M, van Amsterdam FT, Ratti E, Trist DG, Bowery NG. Regionally different N-methyl-D-aspartate receptors distinguished by ligand binding and quantitative autoradiography of [3H]-CGP 39653 in rat brain. Br J Pharmacol. 1996 Nov;119(5):819-28. PubMed PMID: 8922727; PubMed Central PMCID: PMC1915925.
3. White BH, Vogel MW. CGP 39653 binding in the chick CNS after NMDA receptor antagonist treatment. J Neural Transm (Vienna). 1996;103(11):1247-53. PubMed PMID: 9013411.
4. Balcar VJ, Dias LS, Li Y, Bennett MR. Inhibition of [3H]CGP 39653 binding to NMDA receptors by a P2 antagonist, suramin. Neuroreport. 1995 Dec 29;7(1):69-72. PubMed PMID: 8742419.