CL 277082
| Code | Size | Price |
|---|
| TAR-T30961-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
CL 277082 is a boichemical.
CAS:
96224-26-9
Formula:
C26H36F2N2O
Molecular Weight:
430.584
Purity:
0.98
SMILES:
CCCCCCCN(Cc1ccc(CC(C)(C)C)cc1)C(=O)Nc1ccc(F)cc1F
References
1. Pal S, Allister E, Thomson A, Mamo JC. Cholesterol esters regulate apoB48 secretion in CaCo2 cells. Atherosclerosis. 2002 Mar;161(1):55-63. PubMed PMID: 11882317.
2. Kusunoki J, Aragane K, Kitamine T, Yamaura T, Ohnishi H. [Effect of F-1394, a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), on esterification of cholesterol and basolateral secretion of cholesteryl ester in Caco-2 cells]. Nihon Yakurigaku Zasshi. 1997 Dec;110(6):357-65. Japanese. PubMed PMID: 9503394.
3. Ellsworth JL, Starr JR. Inhibition of acyl coenzyme A:cholesterol acyltransferase blocks esterification but not uptake of cholesterol in Caco-2 cells. Metabolism. 1998 Mar;47(3):325-32. PubMed PMID: 9500571.
4. Hawke RL, Chapman JM, Winegar DA, Salisbury JA, Welch RM, Brown A, Franzmann KW, Sigel C. Potent hypocholesterolemic activity of novel ureido phenoxyisobutyrates correlates with their intrinsic fibrate potency and not with their ACAT inhibitory activity. J Lipid Res. 1997 Jun;38(6):1189-203. PubMed PMID: 9215547.